What is theophylline? Theophylline is a bronchodilator that is used to treat symptoms of asthma, bronchitis, emphysema, and other breathing problems. Theophylline may also be used for purposes not listed in this medication guide Theophylline is used to treat lung diseases such as asthma and COPD (bronchitis, emphysema). It must be used regularly to prevent wheezing and shortness of breath Theophylline is used to treat the symptoms of asthma or other lung conditions that block your airways, such as emphysema or chronic bronchitis. Theophylline may be used as part of a combination. Theophylline | C7H8N4O2 | CID 2153 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more

Theophylline - Gyógyszerkereső A kereséshez írja be a keresendő gyógyszer nevét, hatóanyagát, esetleg valamely tulajdonságát! Gyógyszernevek között kere Theophylline is structurally classified as a methylxanthine. It occurs as a white, odorless, crystalline powder with a bitter taste. Anhydrous Theophylline has the chemical name 1 H- Purine -2, 6-dione, 3,7-dihydro-1, 3-dimethyl-, and is represented by the following structural formula: C 7 H 8 N 4 O 2 M.W. 180.17 Theophylline is used to prevent and treat wheezing, shortness of breath, and chest tightness caused by asthma, chronic bronchitis, emphysema, and other lung diseases. It relaxes and opens air passages in the lungs, making it easier to breathe Theophylline in overdose can cause vomiting (which may be severe and intractable), agitation, restlessness, dilated pupils, sinus tachycardia, and hyperglycaemia. More serious effects are haematemesis, convulsions, and supraventricular and ventricular arrhythmias. Severe hypokalaemia may develop rapidly

Theophylline Uses, Side Effects & Warnings - Drugs

  1. ophylline)..
  2. Theophylline and other methylxanthines also display a pharmacological effect on a number of other organ systems. Of course the most pronounced effect is relaxation of smooth musculature in the respiratory tract. However, theophylline is a CNS stimulant, and it lowers arterial blood pressure, increases diuresis, displays cardiotonic activity.
  3. Theophylline extended-release capsules are available in 100-mg, 200-mg, 300-mg, and 400-mg formulations. Theophylline oral suspension is available in an 80-mg per 15-milliliter (80 mg/15 mL) formulation that is typically for use in younger children
  4. Theophylline is used to treat lung diseases such as asthma and COPD (bronchitis, emphysema).It must be used regularly to prevent wheezing and shortness of breath.This medication belongs to a class of drugs known as xanthines. It works in the airways by relaxing muscles, opening breathing passages, and decreasing the lungs' response to irritants. Controlling symptoms of breathing problems can.
  5. Theophylline is a weak nonselective inhibitor of phosphodiesterase (PDE) isoenzymes, which break down cyclic nucleotides in the cell, leading to increased intracellular concentrations of cAMP and cyclic 3′,5′ guanosine monophosphate concentrations ().However, the degree of inhibition is small at therapeutic concentrations
  6. Theophylline can be used as an add-on therapy in the treatment of asthma. Theophylline is taken orally and all available brands are modified release preparations. When prescribing theophylline, the brand should be specified on the prescription
  7. e release. It is used for the treatment of symptoms of reversible airway obstruction secondary to chronic obstructive pulmonary disease, asthma, or chronic bronchitis..

Theophylline Oral : Uses, Side Effects, Interactions

Theophylline is also thought to increase contraction of the diaphragm muscles. Because of theophylline's similarity in structure to caffeine, it produces a well-known caffeine-like side effect profile such as insomnia, nausea, and headache. Serious adverse effects can occur at higher doses especially in overdoses Theophylline is a widely available medication which may further improve lung function and exercise performance. Previous studies evaluating the effects of theophylline on exercise capacity in.

Theophylline is used in the treatment of reversible airway obstruction due to chronic asthma, chronic bronchitis, or COPD. Both the bronchodilator and the adverse effects are closely related to drug concentration. Theophylline is well absorbed when taken orally as a rapid-release tablet or when administered as a liquid solution Theophylline relaxes the smooth muscle of the bronchial airways and pulmonary blood vessels and reduces airway responsiveness to histamine, methacholine, adenosine, and allergen. Theophylline competitively inhibits type III and type IV phosphodiesterase (PDE), the enzyme responsible for breaking down cyclic AMP in smooth muscle cells, possibly resulting in bronchodilation

Child: Individualise dosing based on serum theophylline levels; use ideal body weight to calculate dose. As theophylline monohydrate modified-release tab: ≥6 years Usual maintenance dose: 9 mg/kg bid. As theophylline (anhydrous) modified-release tab/cap: 6-12 years 20-35 kg: 125-250 mg bid; >12 years Same as adult dose. Dosage requirement must be guided by the patient's serum theophylline concentrations, safety, and tolerability (refer to detailed product guideline) Theophylline is a drug derived from methylxanthine (a purine derivative) and has smooth muscle relaxant, bronchial dilation, diuretic, cardiac and central nervous system (CNS) stimulant activities. Naturally present in tea and cocoa beans in small amounts, it was initially extracted and synthesized in 1895 and used as a diuretic theophylline = water soluble aminophylline derivative; cAMP phosphodiesterase inhibitors; used to treat asthma; minimal efficacy with a number of adverse side effects -> some emerging data that useful in the critically ill patient; caffeine -> used in prevention of neonatal apnoea; CLINICAL FEATURES. Theophylline

In COPD, low-dose theophylline is the first drug to demonstrate clear anti-inflammatory effects, and thus it may even have a role in preventing progression of the disease. Furthermore, the reversal of the steroid resistance induced by oxidative stress suggests that theophylline may increase responsiveness to corticosteroids Theophylline (dimethylxanthine) has been used to treat airway diseases for more than 80 years. It was originally used as a bronchodilator, but the relatively high doses required are associated with frequent side effects, so its use declined as inhaled β2-agonists became more widely used. More recent Noun. theophylline ( uncountable ) ( organic chemistry, pharmacology) A bitter crystalline compound present in small quantities in tea leaves, isomeric with theobromine; used as a drug in therapy for respiratory diseases Theophylline EC Number: 200-385-7 EC Name: Theophylline CAS Number: 58-55-9 Molecular formula: C7H8N4O2 IUPAC Name: 1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dion

theophylline + a demethylated methyl donor -> 3-methylxanthine + a methylated methyl donor PlantCyc CPD-12479: Theophylline is a methylated xanthine derivative; competitive nonselective phosphodiesterase inhibitor and nonselective adenosine receptor antagonist Administration. • For I.V. delivery, use infusion solution designed for drug, or mix with dextrose 5% in water. Administer by controlled infusion pump. • Know that for acute bronchospasm, theophylline preferably is given I.V. as 20 mg/ml of theophylline (or 25 mg/ml of aminophylline) Theophylline is a bronchodilator that's been used in the treatment of COPD for more than seven decades.It is used to treat wheezing or shortness of breath caused by asthma, bronchitis, emphysema and other breathing disorders. It works by relaxing the muscles in the lungs and chest, making it easier to breathe Theophylline has also been used as an internal standard for the measurement of plasma paracetamol levels in humans. Packaging 1 kg in poly bottle 50, 100, 250 g in poly bottle Biochem/physiol Actions Theophylline is a tea alkaloid that functions as a nonselective PDE4 inhibitor Theophylline is a bronchodilator that is used to treat symptoms of asthma, bronchitis, emphysema, and other breathing problems. Theophylline may also be used for purposes not listed in this.

Theophylline Side Effects, Dosage, Uses & Mor

Theophylline is rapidly distributed and has a small volume of distribution (~0.5 L/kg). Metabolism: Theophylline is metabolised by cytochrome P450 liver enzymes (mostly 1A2, 3A4, and 2E1 isozymes) and has active (e.g. 1,3-dimethyluric acid) and inactive (e.g. methyl xanthine, 1-methyl uric acid) metabolites Theophylline definition: a white crystalline slightly water-soluble alkaloid that is an isomer of theobromine : it... | Meaning, pronunciation, translations and example Theophylline, alkaloidal drug used in medicine as an antiasthmatic, coronary vasodilator, and diuretic. Theophylline is a xanthine alkaloid, a methylxanthine chemically related to caffeine and theobromine. Along with caffeine, it is an active constituent of tea (Camellia sinensis), but it i Aminophylline and theophylline are medicines used to treat lung diseases such as asthma. They help prevent and treat wheezing and other breathing problems, including respiratory distress associated with premature birth. Aminophylline or theophylline overdose occurs when someone takes more than the normal or recommended amount of these medicines.

Theophylline, also known as dimethylxanthine, is a methylxanthine drug used in therapy for respiratory diseases such as COPD or asthma under a variety of brand names. Due to its numerous side-effects, these drugs are now rarely administered for clinical use. As a member of the xanthine family, it bears structural and pharmacological similarity to caffeine Uses. Theophylline is used to treat lung diseases such as asthma and COPD (bronchitis, emphysema).It must be used regularly to prevent wheezing and shortness of breath. This medication belongs to.

Theophylline dilates the blood vessels of the heart and the bronchial musculature and excites the central nervous system. It is prescribed internally, in powder form, and rectally, as suppositories. It is a constituent of Teofedrin and other compound preparations. It is obtained by chemical synthesis from dimethylurea and ethyl cyanoacetate Search results for theophylline at Sigma-Aldrich. Compare Products: Select up to 4 products. *Please select more than one item to compar Theophylline is a natural alkaloid derivative of xanthine isolated from the plants Camellia sinensis and Coffea arabica. Theophylline appears to inhibit phosphodiesterase and prostaglandin production, regulate calcium flux and intracellular calcium distribution, and antagonize adenosine.Physiologically, this agent relaxes bronchial smooth muscle, produces vasodilation (except in cerebral. Theophylline definition, a white, crystalline, poisonous alkaloid, C7H8N4O2, an isomer of theobromine, extracted from tea leaves or produced synthetically: used to relieve bronchial spasms, in the treatment of certain heart conditions, and as a diuretic. See more

Theophylline is rapidly and completely absorbed in solution or immediate-release. Theophylline C max is 10 mcg/mL (range, 5 to 15 mcg/mL) and T max is 1 to 2 h. Food and antacids do no cause any clinically significant changes. The therapeutic range is 10 to 20 mcg/mL. Distribution Theophylline is approximately 40% protein bound (primarily to. theophylline: ChEBI ID CHEBI:28177: Definition A dimethylxanthine having the two methyl groups located at positions 1 and 3. It is structurally similar to caffeine and is found in green and black tea. Stars This entity has been manually annotated by the ChEBI Team..

THEOPHYLLINE is a bronchodilator. It helps open up the airways in your lungs to make it easier to breathe. This medicine is used to treat the symptoms of asthma, bronchitis, and emphysema. The lowest GoodRx price for the most common version of theophylline ER is around $63.80, 78% off the average retail price of $294.90 Define theophylline. theophylline synonyms, theophylline pronunciation, theophylline translation, English dictionary definition of theophylline. n. A colorless crystalline alkaloid, C7H8N4O2, derived from tea leaves or made synthetically, used as a bronchodilator primarily to treat asthma and chronic.. Theophylline and caffeine tests are used to monitor the amount of the drugs in the blood to establish appropriate doses, maintain therapeutic levels, and evaluate toxicity. Theophylline is usually ordered as a trough level - prior to the next dose when the concentration is expected to be at its lowest level

Theophylline (1,3-dimethylxanthine) can indirectly stimulate both β 1 and β 2 receptors through release of endogenous catecholamines. It is used for the treatment of pulmonary conditions, including asthma and chronic obstructive pulmonary disease (COPD). In neonates, theophylline can be used for the treatment of apnea Theophylline is a medication closely related to caffeine. It relaxes the muscles in the airways (bronchodilator), increases the strength of the muscles involved with breathing, and improves how well mucus and debris are removed from the lungs. Uses/Indications theophylline. A Wikiszótárból, a nyitott szótárból. Ugrás a navigációhoz Ugrás a kereséshez. Angol Főnév. theophylline. teofillin; A lap eredeti címe:.

Theophylline C7H8N4O2 - PubChe

  1. theophylline [the-of€´ĭ-lin] an alkaloid derived from tea or produced synthetically; it is a smooth muscle relaxant used chiefly for its bronchodilator effect in the treatment of chronic obstructive pulmonary disease, emphysema, bronchial asthma, chronic bronchitis, and bronchospastic distress. It also has myocardial stimulant, coronary vasodilator.
  2. theophylline (thee-off-i-lin) Apo-Theo LA, Elixophyllin, Novo-Theophyl SR, PMS-Theophylline, Pulmophylline, Quibron-T, Theochron, Theo-24, Uniphyl. Classification. Therapeutic: bronchodilators. Pharmacologic: xanthines + + Indications + + Long-term control of reversible airway obstruction caused by asthma or COPD. +
  3. Barnes (2003) Theophylline. New perspectives for an old drug. New perspectives for an old drug. Am.J.Respir.Care Med. 167 81
  4. Theophylline E.R. is not FDA approved for use in veterinary medicine however, it is a commonly accepted practice for veterinarians to prescribe this medication for dogs and cats. Theophylline E.R. is used in the treatment of heart failure, pulmonary edema, bronchial asthma, and chronic obstructive pulmonary disease
  5. Theophylline is a very effective bronchodilator medicine. It relaxes the smooth muscles of the airways leading to the lung. This medicine is used to prevent and treat wheezing, shortness of breath, chest tightness associated with lung diseases like asthma, chronic bronchitis, emphysema etc. QUICK LINKS
  6. How theophylline works. Theophylline is a bronchodilator, which means that it relaxes the muscles in your airways so that air passes through easier. It also blocks your body's tendency to tighten the airways when they get irritated, and helps strengthen breathing muscles

Theophylline and its derivatives have been used in the treatment of asthma for over 50 years, but since the advent of more potent bronchodilators their use has become cloaked in controversy. Their continued existence results from their undoubted usefulness in severe acute asthma, nocturnal asthma, childhood asthma and moderate to severe chronic airflow limitation, and because of habitual use. Theophylline (TP) is a bronchodilator used orally to treat Chronic Obstructive Pulmonary Disease (COPD) that has been associated with multiple side effects, tempering its present use. This study aims to improve COPD treatment by creating a low-dose pressurized metered dose inhaler (pMDI) inhalable formulation of Theophylline Theophylline was historically used as primary treatment for asthma but its use has become rare due to the availability and better tolerability of alternative treatments for asthm theophylline - a colorless crystalline alkaloid derived from tea leaves or made synthetically; used in medicine as a bronchial dilator Elixophyllin , Slo-Bid , Theobid bronchodilator - a drug that relaxes and dilates the bronchial passageways and improves the passages of air into the lung

Theophylline extended-release tablets are recommended for chronic or long-term management and prevention of symptoms, and not for use in treating acute symptoms of asthma and reversible bronchospasm. General Consideration Etophylline+Theophylline Tablet is used for Difficulty in breathing, Asthma, Chest tightness, Wheezing, Shortness of breath, Chronic asthma, Breath shortness, Interruption of breathing in newborns, Breathing difficulty, Acute left ventricular failure and other conditions. Etophylline+Theophylline Tablet may also be used for purposes not listed in this medication guide

- theophylline level not declining - clinical symptoms cannot be explained solely by theophylline level. Chronic intoxication - sicker at lower levels (40 - 60 mcg/ml) - MAT, A fib due to underlying disease - Seizures at lower levels - lack of electrolyte abnormalities (K, acidosis) - cardiac toxicity due to overstimulation of myocardium. Serum theophylline levels should be maintained at less than 10 mcg/ml in neonates and less than 20 mcg/ml in older infants. After loading dose of 1 mg/kg P.O. or I.V. for each 2 mcg/ml increase in theophylline level, infants ages 8 weeks to 6 months receive 1 to 3 mg/kg q 6 hours Theophylline relaxes the muscles around the airways in the lungs so air can flow more easily into the lungs. Theophylline may also help the improve contraction of the diaphragm, which may help a persons breathing. Question: Are some theophylline preparations better than others? Answer: A preparation containing only theophylline is considered. Theophylline is a nonselective phosphodiesterase (PDE) inhibitor, adenosine receptor blocker, and histone deacetylase (HDAC) activator. - Mechanism of Action & Protocol Manus Aktteva Biopharma LLP, a global supplier of Theophylline, 58-55-9 offers for your requirements of RND / Development quantities or commercials, based on status of the product. We can also offer its intermediates with supportive technical package required for evaluation

Theophylline tartalmú gyógyszerek - WEBBete

Herbs high in tannins can impair the absorption of theophylline. High-tannin herbs include green tea , black tea, uva ursi (Arctostaphylos uva-ursi), black walnut (Juglans nigra), red raspberry (Rubus idaeus), oak (Quercus spp.), and witch hazel (Hamamelis virginiana). Cruciferous Vegetables. Low-carbohydrate, high-protein diets, charbroiled beef,. Theophylline is usually taken twice a day, although some doctors may prescribe just one dose a day. Take the tablets/capsules exactly as your doctor tells you to. For twice daily doses, always try to take your doses 12 hours apart and at the same times each day. For example, at 8 am and 8 pm each day Drug Name Active Ingredients Strength Dosage Form/Route Marketing Status TE Code RLD RS; THEOPHYLLINE: THEOPHYLLINE: 600MG: TABLET, EXTENDED RELEASE; ORAL: Prescriptio License: Except as otherwise noted, this work is licensed under a Creative Commons Attribution-Noncommercial-Share Alike 4.0 License.For commercial use or customized versions, please contact biobyte solutions GmbH.. Disclaimer: The content of this database of side effects (adverse drug reactions) is intended for educational and scientific research purposes only

Theophylline - FDA prescribing information, side effects

In patients with theophylline overdose who are at high risk for theophylline-induced seizures, e.g., patients with acute overdoses and serum theophylline concentrations > 100 mcg/mL or chronic overdosage in patients > 60 years of age with serum theophylline concentrations > 30 mcg/mL, the need for anticonvulsant therapy should be anticipated Theophylline(Aquaphyllin) generic is a bronchodilator, prescribed for asthma, chronic bronchitis, emphysema, and other lung diseases. It works by relaxing the muscle around the airways in the lungs THEOPHYLLINE (the OFF i lin) is a bronchodilator. It helps open up the airways in your lungs to make it easier to breathe. This medicine is used to treat the symptoms of asthma, bronchitis, and emphysema What is theophylline? Theophylline (brand names: Theo-24®, Theochron®, Elixophyllin®, Theodur®) is a bronchodilator used to treat coughs caused by bronchospasm or bronchoconstriction. It also has mild diuretic effects. Its use in cats and dogs to treat cough and bronchoconstriction is 'off label' or 'extra label.Many drugs are commonly prescribed for off label use in veterinary medicine THEO : Theophylline and its congener, aminophylline, are used to relax smooth muscles of the bronchial airways and pulmonary blood vessels to relieve and prevent symptoms of asthma and bronchospasm. Theophylline is typically administered orally at a dose of 400 mg/day or 6 mg/kg, whichever is lower, or intravenously as aminophylline at 0.4 mg/kg/hour

Theophylline reduces inflammation or irritation in lungs and airways, relaxes smooth muscles in the airways and digestive system, and stimulates the central nervous system. But theophylline can be harmful in high doses or if the theophylline level in your blood is too high, so your healthcare provider may want to test your level of theophylline Theophylline is a prescription medication used to treat airway spasms (called bronchospasms). Bronchospasms are most common in people with asthma but can also occur in people with chronic obstructive pulmonary disease (), which includes chronic bronchitis and emphysema This chapter is concerned with how laboratory measurement of drug concentration in blood helps in determining correct drug dose. Such an approach is either unnecessary or unsuitable for most drug therapies, but for a limited number of drugs including lithium, digoxin and theophylline, measurement of serum or plasma concentration is the preferred method of optimising dosage and preventing. Theophylline is found in black tea and to a lesser extent in green coffee, cocoa cotyledon and dried mate. Theophylline is synthesized on an industrial scale and is used principally in pharmaceutical preparations. Per-caput daily intake of theophylline from black tea in the USA has been estimated to be 0.14 mg www.uptodate.co

Theophylline: MedlinePlus Drug Informatio

See Also: Toxicological Abbreviations Theophylline (IARC Summary & Evaluation, Volume 51, 1991). The molecular mechanism for the anti-inflammatory action of theophylline is currently unknown, but low-dose theophylline is an effective add-on therapy to corticosteroids in controlling asthma. Corticosteroids act, at least in part, by recruitment of histone deacetylases (HDACs) to the site of active inflammatory gene transcription. They thereby inhibit the acetylation of core histones that is. Theophylline es un broncodilatador que se usa para tratar síntomas de asma, la bronquitis, el enfisema, y otros problemas respiratorios. Theophylline puede también usarse para fines no mencionados en esta guía del medicamento Learn how to say Theophylline with EmmaSaying free pronunciation tutorials. Definition and meaning can be found here: https://www.google.com/search?q=define+.. Kiejtési kalauz: Ismerd meg, hogyan ejtik ezt:theophylline angol nyelven, anyanyelvi kiejtéssel! theophylline angol fordítása

The molecular formula of anhydrous theophylline is C 7 H 8 N 4 O 2 with a molecular weight of 180.17.. Theo-24 is available as capsules intended for oral administration, containing 100 mg, 200 mg, 300 mg, or 400 mg of anhydrous theophylline per capsule, in an extended-release formulation which allows a 24-hour dosing interval for appropriate patients {{configCtrl2.info.metaDescription} Theophylline has been studied thoroughly in clinical trials. In these studies, the side effects that occur in a group of people taking the drug are documented and are then compared to side effects that occur in another group of people not taking the medication

THEOPHYLLINE Drug BNF content published by NIC

theophylline is a topic covered in the Davis's Drug Guide.. To view the entire topic, please sign in or purchase a subscription.. Nursing Central is an award-winning, complete mobile solution for nurses and students. Look up information on diseases, tests, and procedures; then consult the database with 5,000+ drugs or refer to 65,000+ dictionary terms Theophylline is structurally classified as a methylxanthine. It occurs as a white, odorless, crystalline powder with a bitter taste. Anhydrous theophylline has the chemical name 1HPurine- 2,6-dione, 3,7-dihydro-1,3-dimethyl-, and is represented by the following structural formula Theophylline (200 mg) THIS ITEM HAS BEEN IDENTIFIED AS A POTENTIALLY DANGEROUS GOOD. SPECIAL SHIPPING METHODS AND CHARGES MAY APPLY. Catalog # 1653004: Current Lot R084X0: Previous Lot J1H052 (Valid Use Date: 31-MAR-2019) SDS View: USP Certificate for Current Lot View: CAS# 58-55-9: In Stock. Description. Theophylline is a bronchodilator, which means it's a substance that works to open up airways. It's used to help ease breathing in those who suffer from respiratory disorders that arise from heart failure, pulmonary edema, bronchial asthma, chronic obstructive pulmonary disease (COPD) and other disorders

Theophylline Asthma U

Search results for theophylline 7 results found Save this search. Page 1 of 1; Filter Search Results. Sort by. Medicine Information for... Healthcare Professionals (SmPC) Patients (PIL) Discontinued Medicines Includes patient information for visually impaired. theophylline anhydrous fordítása a angol - magyar szótárban, a Glosbe ingyenes online szótárcsaládjában. Böngésszen milliónyi szót és kifejezést a világ minden nyelvén Theophylline is a xanthine derivative used in the treatment of asthma and stable COPD to relax the bronchial smooth muscle. It has a narrow therapeutic index; a serum theophylline concentration of 10-20mg/L is required in the majority of patients, although some may find lower theophylline levels to be sufficient to control their symptoms Pesticide properties for Theophylline, including approvals, environmental fate, eco-toxicity and human health issue Theophylline is a bronchodilator that is used to treat symptoms of asthma, bronchitis, emphysema, and other breathing problems.. Theophylline may also be used for purposes not listed in this medication guide

Pharmacology of the respiratory system - презентация онлайнMolecules | Free Full-Text | Structure-BioactivitySunovion's New Drug Application for COPD Therapy Accepted
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